Genetic Test
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) encodes a channel protein that functions as a passageway for ions moving into and out of cells. Mutations in this gene are particularly associated with cartilage abnormalities in Scottish Fold cats. This genetic test targets one specific gene variant related to osteochondrodysplasia.
Disease Description
One of the most distinctive features of Scottish Fold cats is their adorable forward-folded ears. However, this characteristic results from a genetic defect that impairs the proper development of ear cartilage. This abnormality is not limited to the ears but also affects cartilage and bone development throughout the body. Such skeletal and cartilage deformities can lead to severe and painful arthritis.
