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Factor IX Deficiency (Hemophilia B)

Genetic Test

The F9 (Coagulation Factor IX) gene encodes coagulation factor IX, a vitamin K-dependent protein essential for blood clotting. This protein circulates in the bloodstream and plays a key role in activating the coagulation cascade to prevent excessive bleeding. Mutations in the F9 gene cause factor IX deficiency, also known as hemophilia B. This genetic test targets a specific mutation associated with factor IX deficiency.

Disease Description

Factor IX deficiency is a hereditary bleeding disorder caused by impaired blood clotting due to a deficiency of coagulation factor IX. This condition is also known as hemophilia B. Affected animals may suffer from prolonged bleeding at sites of trauma, the umbilical cord after birth, and spontaneous bleeding from the nose, mouth, eyes, and other areas.